Amino acid dipepetide frequency for Giant panda polyomavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.796AlaAla: 5.796 ± 1.567
2.107AlaCys: 2.107 ± 1.55
3.161AlaAsp: 3.161 ± 0.419
2.634AlaGlu: 2.634 ± 1.048
2.107AlaPhe: 2.107 ± 0.669
4.215AlaGly: 4.215 ± 0.962
0.0AlaHis: 0.0 ± 0.0
4.215AlaIle: 4.215 ± 0.727
1.581AlaLys: 1.581 ± 1.407
4.742AlaLeu: 4.742 ± 1.944
1.054AlaMet: 1.054 ± 0.705
0.527AlaAsn: 0.527 ± 0.469
3.161AlaPro: 3.161 ± 1.0
2.634AlaGln: 2.634 ± 1.667
6.849AlaArg: 6.849 ± 2.969
5.269AlaSer: 5.269 ± 2.161
3.688AlaThr: 3.688 ± 1.215
4.742AlaVal: 4.742 ± 1.673
1.054AlaTrp: 1.054 ± 0.775
2.107AlaTyr: 2.107 ± 0.482
0.0AlaXaa: 0.0 ± 0.0
Cys
1.054CysAla: 1.054 ± 0.383
1.581CysCys: 1.581 ± 1.084
1.581CysAsp: 1.581 ± 0.763
1.054CysGlu: 1.054 ± 0.775
1.581CysPhe: 1.581 ± 0.86
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.581CysIle: 1.581 ± 2.222
3.161CysLys: 3.161 ± 1.691
4.215CysLeu: 4.215 ± 2.812
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.581CysPro: 1.581 ± 0.763
0.527CysGln: 0.527 ± 0.388
0.0CysArg: 0.0 ± 0.0
2.107CysSer: 2.107 ± 0.622
1.054CysThr: 1.054 ± 0.703
0.527CysVal: 0.527 ± 0.741
0.0CysTrp: 0.0 ± 0.0
2.107CysTyr: 2.107 ± 1.406
0.0CysXaa: 0.0 ± 0.0
Asp
3.161AspAla: 3.161 ± 0.933
0.527AspCys: 0.527 ± 0.388
0.527AspAsp: 0.527 ± 0.388
4.742AspGlu: 4.742 ± 1.942
2.634AspPhe: 2.634 ± 1.461
3.688AspGly: 3.688 ± 0.986
0.527AspHis: 0.527 ± 0.388
4.742AspIle: 4.742 ± 1.719
3.161AspLys: 3.161 ± 1.154
6.849AspLeu: 6.849 ± 0.979
1.581AspMet: 1.581 ± 0.763
1.054AspAsn: 1.054 ± 0.775
4.215AspPro: 4.215 ± 1.899
3.161AspGln: 3.161 ± 1.207
0.527AspArg: 0.527 ± 0.469
5.269AspSer: 5.269 ± 2.155
2.634AspThr: 2.634 ± 1.505
1.054AspVal: 1.054 ± 0.775
2.634AspTrp: 2.634 ± 1.451
2.107AspTyr: 2.107 ± 0.949
0.0AspXaa: 0.0 ± 0.0
Glu
4.215GluAla: 4.215 ± 1.969
1.054GluCys: 1.054 ± 0.703
5.269GluAsp: 5.269 ± 2.108
6.849GluGlu: 6.849 ± 1.238
0.527GluPhe: 0.527 ± 0.388
2.634GluGly: 2.634 ± 1.887
1.581GluHis: 1.581 ± 0.523
2.107GluIle: 2.107 ± 0.669
5.796GluLys: 5.796 ± 3.226
4.215GluLeu: 4.215 ± 1.147
0.0GluMet: 0.0 ± 0.0
3.161GluAsn: 3.161 ± 1.223
2.107GluPro: 2.107 ± 1.097
0.0GluGln: 0.0 ± 0.0
2.107GluArg: 2.107 ± 1.264
5.796GluSer: 5.796 ± 2.105
4.215GluThr: 4.215 ± 1.815
5.269GluVal: 5.269 ± 1.588
1.054GluTrp: 1.054 ± 0.703
1.581GluTyr: 1.581 ± 0.523
0.0GluXaa: 0.0 ± 0.0
Phe
2.107PheAla: 2.107 ± 0.949
1.054PheCys: 1.054 ± 0.703
2.107PheAsp: 2.107 ± 0.669
1.581PheGlu: 1.581 ± 0.86
2.107PhePhe: 2.107 ± 0.992
3.161PheGly: 3.161 ± 2.023
2.107PheHis: 2.107 ± 0.773
1.581PheIle: 1.581 ± 0.611
1.581PheLys: 1.581 ± 1.163
2.107PheLeu: 2.107 ± 1.55
0.527PheMet: 0.527 ± 0.388
1.581PheAsn: 1.581 ± 0.604
2.634PhePro: 2.634 ± 0.428
4.742PheGln: 4.742 ± 2.332
0.527PheArg: 0.527 ± 0.388
4.742PheSer: 4.742 ± 0.694
1.054PheThr: 1.054 ± 0.705
1.054PheVal: 1.054 ± 0.383
0.0PheTrp: 0.0 ± 0.0
1.054PheTyr: 1.054 ± 0.383
0.0PheXaa: 0.0 ± 0.0
Gly
4.215GlyAla: 4.215 ± 0.963
1.054GlyCys: 1.054 ± 0.775
5.796GlyAsp: 5.796 ± 0.8
4.215GlyGlu: 4.215 ± 1.502
2.634GlyPhe: 2.634 ± 0.875
5.269GlyGly: 5.269 ± 1.402
0.527GlyHis: 0.527 ± 0.469
3.161GlyIle: 3.161 ± 0.72
4.215GlyLys: 4.215 ± 1.244
6.849GlyLeu: 6.849 ± 1.847
0.0GlyMet: 0.0 ± 0.0
1.054GlyAsn: 1.054 ± 0.703
4.742GlyPro: 4.742 ± 1.313
2.634GlyGln: 2.634 ± 1.113
1.054GlyArg: 1.054 ± 0.632
3.688GlySer: 3.688 ± 0.935
1.054GlyThr: 1.054 ± 0.383
7.376GlyVal: 7.376 ± 1.581
0.527GlyTrp: 0.527 ± 0.388
1.054GlyTyr: 1.054 ± 0.938
0.0GlyXaa: 0.0 ± 0.0
His
2.107HisAla: 2.107 ± 1.264
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.581HisGlu: 1.581 ± 0.523
0.527HisPhe: 0.527 ± 0.469
0.527HisGly: 0.527 ± 0.388
0.527HisHis: 0.527 ± 0.741
1.054HisIle: 1.054 ± 0.632
0.527HisLys: 0.527 ± 0.388
0.527HisLeu: 0.527 ± 0.388
0.527HisMet: 0.527 ± 0.469
1.581HisAsn: 1.581 ± 0.611
1.581HisPro: 1.581 ± 0.86
0.527HisGln: 0.527 ± 0.741
1.054HisArg: 1.054 ± 0.383
1.581HisSer: 1.581 ± 0.523
0.0HisThr: 0.0 ± 0.0
0.527HisVal: 0.527 ± 0.388
0.527HisTrp: 0.527 ± 0.741
1.581HisTyr: 1.581 ± 1.391
0.0HisXaa: 0.0 ± 0.0
Ile
1.054IleAla: 1.054 ± 0.938
0.527IleCys: 0.527 ± 0.741
0.527IleAsp: 0.527 ± 0.388
7.376IleGlu: 7.376 ± 3.751
1.054IlePhe: 1.054 ± 0.775
0.527IleGly: 0.527 ± 0.469
0.0IleHis: 0.0 ± 0.0
2.107IleIle: 2.107 ± 0.766
4.215IleLys: 4.215 ± 0.754
4.215IleLeu: 4.215 ± 1.388
1.054IleMet: 1.054 ± 0.775
2.634IleAsn: 2.634 ± 0.961
4.215IlePro: 4.215 ± 0.845
2.634IleGln: 2.634 ± 0.428
0.0IleArg: 0.0 ± 0.0
1.054IleSer: 1.054 ± 0.938
5.269IleThr: 5.269 ± 1.106
4.215IleVal: 4.215 ± 1.257
1.581IleTrp: 1.581 ± 0.523
3.161IleTyr: 3.161 ± 0.837
0.0IleXaa: 0.0 ± 0.0
Lys
4.215LysAla: 4.215 ± 1.244
1.054LysCys: 1.054 ± 0.775
2.634LysAsp: 2.634 ± 0.842
2.634LysGlu: 2.634 ± 1.315
2.634LysPhe: 2.634 ± 2.076
4.215LysGly: 4.215 ± 1.025
2.107LysHis: 2.107 ± 1.134
1.054LysIle: 1.054 ± 0.775
6.849LysLys: 6.849 ± 2.195
3.161LysLeu: 3.161 ± 0.756
3.161LysMet: 3.161 ± 0.756
3.161LysAsn: 3.161 ± 0.756
1.054LysPro: 1.054 ± 0.802
3.688LysGln: 3.688 ± 0.621
5.269LysArg: 5.269 ± 0.851
3.688LysSer: 3.688 ± 0.935
6.322LysThr: 6.322 ± 0.955
2.107LysVal: 2.107 ± 1.134
0.0LysTrp: 0.0 ± 0.0
2.634LysTyr: 2.634 ± 1.523
0.0LysXaa: 0.0 ± 0.0
Leu
5.796LeuAla: 5.796 ± 1.486
1.581LeuCys: 1.581 ± 0.604
7.376LeuAsp: 7.376 ± 1.744
5.796LeuGlu: 5.796 ± 1.723
6.322LeuPhe: 6.322 ± 1.829
6.322LeuGly: 6.322 ± 2.072
1.581LeuHis: 1.581 ± 0.86
3.161LeuIle: 3.161 ± 0.72
3.688LeuLys: 3.688 ± 1.163
12.118LeuLeu: 12.118 ± 3.746
5.796LeuMet: 5.796 ± 0.785
5.796LeuAsn: 5.796 ± 1.82
6.849LeuPro: 6.849 ± 2.568
2.634LeuGln: 2.634 ± 0.944
4.742LeuArg: 4.742 ± 1.103
5.796LeuSer: 5.796 ± 1.738
4.742LeuThr: 4.742 ± 0.73
4.215LeuVal: 4.215 ± 1.089
0.527LeuTrp: 0.527 ± 0.741
1.581LeuTyr: 1.581 ± 0.523
0.0LeuXaa: 0.0 ± 0.0
Met
3.161MetAla: 3.161 ± 1.057
0.527MetCys: 0.527 ± 0.388
2.107MetAsp: 2.107 ± 0.622
2.107MetGlu: 2.107 ± 0.821
0.527MetPhe: 0.527 ± 0.469
2.107MetGly: 2.107 ± 0.92
0.0MetHis: 0.0 ± 0.0
1.581MetIle: 1.581 ± 0.763
2.107MetLys: 2.107 ± 1.134
2.107MetLeu: 2.107 ± 0.895
1.054MetMet: 1.054 ± 0.41
0.527MetAsn: 0.527 ± 0.388
3.161MetPro: 3.161 ± 1.212
2.107MetGln: 2.107 ± 0.622
1.054MetArg: 1.054 ± 0.632
1.054MetSer: 1.054 ± 0.703
0.527MetThr: 0.527 ± 0.469
1.054MetVal: 1.054 ± 0.775
0.527MetTrp: 0.527 ± 0.469
1.054MetTyr: 1.054 ± 0.938
0.0MetXaa: 0.0 ± 0.0
Asn
1.054AsnAla: 1.054 ± 0.775
2.634AsnCys: 2.634 ± 2.076
1.581AsnAsp: 1.581 ± 0.611
1.581AsnGlu: 1.581 ± 0.763
0.527AsnPhe: 0.527 ± 0.388
1.581AsnGly: 1.581 ± 0.763
2.107AsnHis: 2.107 ± 0.949
4.742AsnIle: 4.742 ± 0.73
2.107AsnLys: 2.107 ± 1.55
4.215AsnLeu: 4.215 ± 2.268
1.054AsnMet: 1.054 ± 0.632
0.0AsnAsn: 0.0 ± 0.0
3.688AsnPro: 3.688 ± 1.657
1.581AsnGln: 1.581 ± 1.407
1.581AsnArg: 1.581 ± 0.763
2.107AsnSer: 2.107 ± 0.622
2.634AsnThr: 2.634 ± 0.842
1.054AsnVal: 1.054 ± 0.938
0.527AsnTrp: 0.527 ± 0.388
1.054AsnTyr: 1.054 ± 0.775
0.0AsnXaa: 0.0 ± 0.0
Pro
2.107ProAla: 2.107 ± 1.097
0.527ProCys: 0.527 ± 0.741
4.742ProAsp: 4.742 ± 0.558
3.688ProGlu: 3.688 ± 1.371
1.054ProPhe: 1.054 ± 0.383
6.322ProGly: 6.322 ± 1.482
0.0ProHis: 0.0 ± 0.0
2.634ProIle: 2.634 ± 0.794
5.796ProLys: 5.796 ± 1.592
6.849ProLeu: 6.849 ± 1.97
2.634ProMet: 2.634 ± 0.723
3.161ProAsn: 3.161 ± 1.148
11.591ProPro: 11.591 ± 4.336
2.634ProGln: 2.634 ± 0.961
3.161ProArg: 3.161 ± 1.616
7.376ProSer: 7.376 ± 2.958
7.376ProThr: 7.376 ± 1.235
4.215ProVal: 4.215 ± 1.423
1.054ProTrp: 1.054 ± 0.632
1.581ProTyr: 1.581 ± 0.611
0.0ProXaa: 0.0 ± 0.0
Gln
3.161GlnAla: 3.161 ± 0.659
0.0GlnCys: 0.0 ± 0.0
4.742GlnAsp: 4.742 ± 1.569
2.107GlnGlu: 2.107 ± 0.766
2.107GlnPhe: 2.107 ± 0.949
1.054GlnGly: 1.054 ± 0.775
1.054GlnHis: 1.054 ± 0.802
1.581GlnIle: 1.581 ± 0.523
2.634GlnLys: 2.634 ± 1.461
3.161GlnLeu: 3.161 ± 1.224
2.107GlnMet: 2.107 ± 1.085
0.0GlnAsn: 0.0 ± 0.0
3.161GlnPro: 3.161 ± 0.756
3.161GlnGln: 3.161 ± 1.271
2.107GlnArg: 2.107 ± 1.264
1.581GlnSer: 1.581 ± 1.163
3.688GlnThr: 3.688 ± 1.215
2.107GlnVal: 2.107 ± 1.196
0.0GlnTrp: 0.0 ± 0.0
2.107GlnTyr: 2.107 ± 0.766
0.0GlnXaa: 0.0 ± 0.0
Arg
5.796ArgAla: 5.796 ± 2.36
0.527ArgCys: 0.527 ± 0.469
2.634ArgAsp: 2.634 ± 0.842
2.634ArgGlu: 2.634 ± 1.094
0.527ArgPhe: 0.527 ± 0.388
3.688ArgGly: 3.688 ± 0.471
1.054ArgHis: 1.054 ± 0.632
2.634ArgIle: 2.634 ± 1.113
3.161ArgLys: 3.161 ± 0.837
4.742ArgLeu: 4.742 ± 1.475
0.527ArgMet: 0.527 ± 0.469
2.634ArgAsn: 2.634 ± 1.094
1.054ArgPro: 1.054 ± 0.383
1.054ArgGln: 1.054 ± 0.632
4.215ArgArg: 4.215 ± 0.875
1.581ArgSer: 1.581 ± 0.86
0.0ArgThr: 0.0 ± 0.0
2.107ArgVal: 2.107 ± 0.482
1.054ArgTrp: 1.054 ± 0.632
3.161ArgTyr: 3.161 ± 1.212
0.0ArgXaa: 0.0 ± 0.0
Ser
3.688SerAla: 3.688 ± 1.751
2.634SerCys: 2.634 ± 0.688
4.215SerAsp: 4.215 ± 1.244
1.581SerGlu: 1.581 ± 0.611
3.161SerPhe: 3.161 ± 0.915
5.269SerGly: 5.269 ± 0.855
0.0SerHis: 0.0 ± 0.0
2.634SerIle: 2.634 ± 0.687
3.688SerLys: 3.688 ± 1.884
11.591SerLeu: 11.591 ± 2.397
1.581SerMet: 1.581 ± 0.763
1.054SerAsn: 1.054 ± 0.775
8.957SerPro: 8.957 ± 2.606
2.634SerGln: 2.634 ± 0.842
3.688SerArg: 3.688 ± 0.993
12.645SerSer: 12.645 ± 1.489
1.581SerThr: 1.581 ± 0.69
3.161SerVal: 3.161 ± 1.081
0.527SerTrp: 0.527 ± 0.741
3.688SerTyr: 3.688 ± 1.215
0.0SerXaa: 0.0 ± 0.0
Thr
3.161ThrAla: 3.161 ± 0.756
2.634ThrCys: 2.634 ± 1.365
0.527ThrAsp: 0.527 ± 0.388
2.107ThrGlu: 2.107 ± 0.821
2.634ThrPhe: 2.634 ± 0.882
1.581ThrGly: 1.581 ± 1.078
1.054ThrHis: 1.054 ± 0.632
3.688ThrIle: 3.688 ± 0.986
1.581ThrLys: 1.581 ± 0.86
5.269ThrLeu: 5.269 ± 0.658
3.161ThrMet: 3.161 ± 0.72
3.161ThrAsn: 3.161 ± 0.598
8.957ThrPro: 8.957 ± 1.4
0.527ThrGln: 0.527 ± 0.388
2.634ThrArg: 2.634 ± 0.428
2.634ThrSer: 2.634 ± 1.113
4.742ThrThr: 4.742 ± 1.253
4.215ThrVal: 4.215 ± 0.216
1.054ThrTrp: 1.054 ± 0.632
2.107ThrTyr: 2.107 ± 1.208
0.0ThrXaa: 0.0 ± 0.0
Val
5.269ValAla: 5.269 ± 1.518
1.054ValCys: 1.054 ± 0.775
2.634ValAsp: 2.634 ± 0.764
2.107ValGlu: 2.107 ± 0.817
1.581ValPhe: 1.581 ± 1.163
2.634ValGly: 2.634 ± 1.505
1.581ValHis: 1.581 ± 0.523
2.107ValIle: 2.107 ± 0.773
3.688ValLys: 3.688 ± 0.935
5.796ValLeu: 5.796 ± 1.069
0.0ValMet: 0.0 ± 0.0
5.269ValAsn: 5.269 ± 0.566
4.215ValPro: 4.215 ± 1.423
3.161ValGln: 3.161 ± 1.046
0.527ValArg: 0.527 ± 0.469
5.796ValSer: 5.796 ± 1.684
3.688ValThr: 3.688 ± 0.621
7.376ValVal: 7.376 ± 2.274
1.054ValTrp: 1.054 ± 0.802
1.581ValTyr: 1.581 ± 0.86
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.527TrpCys: 0.527 ± 0.469
1.054TrpAsp: 1.054 ± 0.632
2.107TrpGlu: 2.107 ± 0.622
0.527TrpPhe: 0.527 ± 0.741
1.581TrpGly: 1.581 ± 0.963
0.0TrpHis: 0.0 ± 0.0
1.054TrpIle: 1.054 ± 0.632
1.054TrpLys: 1.054 ± 0.703
1.054TrpLeu: 1.054 ± 0.703
1.054TrpMet: 1.054 ± 0.887
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.527TrpGln: 0.527 ± 0.388
0.0TrpArg: 0.0 ± 0.0
1.581TrpSer: 1.581 ± 0.523
0.0TrpThr: 0.0 ± 0.0
1.581TrpVal: 1.581 ± 0.523
1.581TrpTrp: 1.581 ± 0.86
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.527TyrAla: 0.527 ± 0.469
2.107TyrCys: 2.107 ± 1.406
1.581TyrAsp: 1.581 ± 0.763
1.054TyrGlu: 1.054 ± 0.632
2.634TyrPhe: 2.634 ± 0.794
4.742TyrGly: 4.742 ± 0.558
1.054TyrHis: 1.054 ± 0.802
0.0TyrIle: 0.0 ± 0.0
1.054TyrLys: 1.054 ± 0.703
2.634TyrLeu: 2.634 ± 0.428
1.054TyrMet: 1.054 ± 0.775
1.054TyrAsn: 1.054 ± 0.703
1.581TyrPro: 1.581 ± 1.407
1.054TyrGln: 1.054 ± 0.775
3.688TyrArg: 3.688 ± 1.125
2.634TyrSer: 2.634 ± 0.794
3.161TyrThr: 3.161 ± 1.223
3.161TyrVal: 3.161 ± 0.598
0.527TyrTrp: 0.527 ± 0.388
1.581TyrTyr: 1.581 ± 0.763
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski