Amino acid dipepetide frequency for Rhesus monkey rhadinovirus H26-95

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.298AlaAla: 7.298 ± 0.639
2.227AlaCys: 2.227 ± 0.288
3.112AlaAsp: 3.112 ± 0.304
3.595AlaGlu: 3.595 ± 0.345
3.515AlaPhe: 3.515 ± 0.315
4.964AlaGly: 4.964 ± 0.702
1.985AlaHis: 1.985 ± 0.225
3.327AlaIle: 3.327 ± 0.306
2.737AlaLys: 2.737 ± 0.312
7.137AlaLeu: 7.137 ± 0.526
1.556AlaMet: 1.556 ± 0.213
2.764AlaAsn: 2.764 ± 0.283
5.822AlaPro: 5.822 ± 0.477
2.361AlaGln: 2.361 ± 0.274
4.293AlaArg: 4.293 ± 0.424
5.661AlaSer: 5.661 ± 0.454
5.956AlaThr: 5.956 ± 0.568
5.527AlaVal: 5.527 ± 0.429
1.073AlaTrp: 1.073 ± 0.174
2.307AlaTyr: 2.307 ± 0.319
0.0AlaXaa: 0.0 ± 0.0
Cys
1.529CysAla: 1.529 ± 0.245
0.778CysCys: 0.778 ± 0.138
0.966CysAsp: 0.966 ± 0.168
1.368CysGlu: 1.368 ± 0.22
1.154CysPhe: 1.154 ± 0.181
1.449CysGly: 1.449 ± 0.212
0.644CysHis: 0.644 ± 0.132
0.993CysIle: 0.993 ± 0.174
1.02CysLys: 1.02 ± 0.165
3.381CysLeu: 3.381 ± 0.332
0.456CysMet: 0.456 ± 0.112
1.127CysAsn: 1.127 ± 0.164
1.503CysPro: 1.503 ± 0.21
1.368CysGln: 1.368 ± 0.175
2.093CysArg: 2.093 ± 0.415
1.583CysSer: 1.583 ± 0.217
1.073CysThr: 1.073 ± 0.15
2.415CysVal: 2.415 ± 0.262
0.268CysTrp: 0.268 ± 0.079
0.617CysTyr: 0.617 ± 0.116
0.0CysXaa: 0.0 ± 0.0
Asp
4.427AspAla: 4.427 ± 0.326
0.859AspCys: 0.859 ± 0.174
3.005AspAsp: 3.005 ± 0.364
2.951AspGlu: 2.951 ± 0.285
2.093AspPhe: 2.093 ± 0.273
2.656AspGly: 2.656 ± 0.27
1.02AspHis: 1.02 ± 0.151
2.388AspIle: 2.388 ± 0.217
1.583AspLys: 1.583 ± 0.231
4.481AspLeu: 4.481 ± 0.407
1.127AspMet: 1.127 ± 0.233
2.093AspAsn: 2.093 ± 0.218
2.764AspPro: 2.764 ± 0.298
1.368AspGln: 1.368 ± 0.167
2.71AspArg: 2.71 ± 0.264
2.737AspSer: 2.737 ± 0.277
2.79AspThr: 2.79 ± 0.268
3.595AspVal: 3.595 ± 0.35
0.644AspTrp: 0.644 ± 0.111
1.395AspTyr: 1.395 ± 0.18
0.0AspXaa: 0.0 ± 0.0
Glu
3.515GluAla: 3.515 ± 0.477
1.476GluCys: 1.476 ± 0.222
2.737GluAsp: 2.737 ± 0.274
2.79GluGlu: 2.79 ± 0.311
1.529GluPhe: 1.529 ± 0.183
2.656GluGly: 2.656 ± 0.238
1.503GluHis: 1.503 ± 0.186
2.844GluIle: 2.844 ± 0.254
2.2GluLys: 2.2 ± 0.269
4.588GluLeu: 4.588 ± 0.328
1.395GluMet: 1.395 ± 0.207
2.468GluAsn: 2.468 ± 0.268
2.334GluPro: 2.334 ± 0.242
1.905GluGln: 1.905 ± 0.244
2.683GluArg: 2.683 ± 0.364
3.542GluSer: 3.542 ± 0.363
4.051GluThr: 4.051 ± 0.395
3.032GluVal: 3.032 ± 0.268
0.429GluTrp: 0.429 ± 0.111
1.637GluTyr: 1.637 ± 0.243
0.0GluXaa: 0.0 ± 0.0
Phe
2.307PheAla: 2.307 ± 0.241
1.1PheCys: 1.1 ± 0.184
1.905PheAsp: 1.905 ± 0.208
1.824PheGlu: 1.824 ± 0.184
2.254PhePhe: 2.254 ± 0.272
2.442PheGly: 2.442 ± 0.295
1.046PheHis: 1.046 ± 0.185
2.522PheIle: 2.522 ± 0.266
2.603PheLys: 2.603 ± 0.328
5.312PheLeu: 5.312 ± 0.448
1.046PheMet: 1.046 ± 0.152
1.717PheAsn: 1.717 ± 0.197
2.683PhePro: 2.683 ± 0.286
1.798PheGln: 1.798 ± 0.211
1.985PheArg: 1.985 ± 0.306
3.032PheSer: 3.032 ± 0.298
2.549PheThr: 2.549 ± 0.247
2.844PheVal: 2.844 ± 0.364
0.617PheTrp: 0.617 ± 0.129
2.146PheTyr: 2.146 ± 0.275
0.0PheXaa: 0.0 ± 0.0
Gly
5.5GlyAla: 5.5 ± 0.803
1.61GlyCys: 1.61 ± 0.433
3.032GlyAsp: 3.032 ± 0.284
2.871GlyGlu: 2.871 ± 0.325
2.844GlyPhe: 2.844 ± 0.268
4.695GlyGly: 4.695 ± 0.933
1.771GlyHis: 1.771 ± 0.236
2.683GlyIle: 2.683 ± 0.299
1.905GlyLys: 1.905 ± 0.276
6.439GlyLeu: 6.439 ± 0.589
1.073GlyMet: 1.073 ± 0.197
2.254GlyAsn: 2.254 ± 0.318
4.025GlyPro: 4.025 ± 0.68
2.334GlyGln: 2.334 ± 0.304
4.266GlyArg: 4.266 ± 0.47
4.803GlySer: 4.803 ± 0.58
4.159GlyThr: 4.159 ± 0.344
4.937GlyVal: 4.937 ± 0.629
0.859GlyTrp: 0.859 ± 0.317
1.529GlyTyr: 1.529 ± 0.241
0.0GlyXaa: 0.0 ± 0.0
His
1.771HisAla: 1.771 ± 0.217
0.617HisCys: 0.617 ± 0.128
1.207HisAsp: 1.207 ± 0.181
1.61HisGlu: 1.61 ± 0.222
0.993HisPhe: 0.993 ± 0.159
2.173HisGly: 2.173 ± 0.27
0.859HisHis: 0.859 ± 0.143
1.315HisIle: 1.315 ± 0.168
1.154HisLys: 1.154 ± 0.169
2.951HisLeu: 2.951 ± 0.364
0.537HisMet: 0.537 ± 0.151
0.912HisAsn: 0.912 ± 0.13
2.066HisPro: 2.066 ± 0.293
0.885HisGln: 0.885 ± 0.139
1.717HisArg: 1.717 ± 0.191
1.422HisSer: 1.422 ± 0.193
1.503HisThr: 1.503 ± 0.307
2.415HisVal: 2.415 ± 0.249
0.268HisTrp: 0.268 ± 0.076
0.778HisTyr: 0.778 ± 0.147
0.0HisXaa: 0.0 ± 0.0
Ile
3.461IleAla: 3.461 ± 0.314
1.503IleCys: 1.503 ± 0.24
1.932IleAsp: 1.932 ± 0.25
2.2IleGlu: 2.2 ± 0.262
2.12IlePhe: 2.12 ± 0.304
2.093IleGly: 2.093 ± 0.198
1.1IleHis: 1.1 ± 0.162
2.361IleIle: 2.361 ± 0.208
2.227IleLys: 2.227 ± 0.236
5.125IleLeu: 5.125 ± 0.488
1.288IleMet: 1.288 ± 0.179
2.683IleAsn: 2.683 ± 0.291
3.005IlePro: 3.005 ± 0.408
2.093IleGln: 2.093 ± 0.243
2.844IleArg: 2.844 ± 0.356
3.756IleSer: 3.756 ± 0.34
3.327IleThr: 3.327 ± 0.387
3.273IleVal: 3.273 ± 0.365
0.402IleTrp: 0.402 ± 0.094
1.529IleTyr: 1.529 ± 0.22
0.0IleXaa: 0.0 ± 0.0
Lys
2.2LysAla: 2.2 ± 0.222
0.724LysCys: 0.724 ± 0.125
1.798LysAsp: 1.798 ± 0.29
1.959LysGlu: 1.959 ± 0.219
1.637LysPhe: 1.637 ± 0.193
1.985LysGly: 1.985 ± 0.239
1.476LysHis: 1.476 ± 0.241
2.683LysIle: 2.683 ± 0.383
2.388LysLys: 2.388 ± 0.281
4.266LysLeu: 4.266 ± 0.42
1.154LysMet: 1.154 ± 0.146
2.093LysAsn: 2.093 ± 0.236
2.066LysPro: 2.066 ± 0.298
1.878LysGln: 1.878 ± 0.22
2.656LysArg: 2.656 ± 0.249
2.468LysSer: 2.468 ± 0.284
3.461LysThr: 3.461 ± 0.327
1.905LysVal: 1.905 ± 0.27
0.322LysTrp: 0.322 ± 0.107
1.02LysTyr: 1.02 ± 0.183
0.0LysXaa: 0.0 ± 0.0
Leu
7.298LeuAla: 7.298 ± 0.452
2.656LeuCys: 2.656 ± 0.295
4.293LeuAsp: 4.293 ± 0.325
5.339LeuGlu: 5.339 ± 0.439
4.856LeuPhe: 4.856 ± 0.464
6.466LeuGly: 6.466 ± 0.584
2.603LeuHis: 2.603 ± 0.299
3.729LeuIle: 3.729 ± 0.273
4.964LeuLys: 4.964 ± 0.397
8.586LeuLeu: 8.586 ± 0.586
1.985LeuMet: 1.985 ± 0.255
4.856LeuAsn: 4.856 ± 0.385
6.064LeuPro: 6.064 ± 0.482
3.729LeuGln: 3.729 ± 0.293
6.547LeuArg: 6.547 ± 0.515
7.727LeuSer: 7.727 ± 0.478
6.761LeuThr: 6.761 ± 0.362
6.305LeuVal: 6.305 ± 0.566
1.261LeuTrp: 1.261 ± 0.207
3.407LeuTyr: 3.407 ± 0.342
0.0LeuXaa: 0.0 ± 0.0
Met
1.905MetAla: 1.905 ± 0.242
0.563MetCys: 0.563 ± 0.122
1.046MetAsp: 1.046 ± 0.182
1.1MetGlu: 1.1 ± 0.186
1.476MetPhe: 1.476 ± 0.268
1.315MetGly: 1.315 ± 0.232
0.59MetHis: 0.59 ± 0.16
1.046MetIle: 1.046 ± 0.196
0.671MetLys: 0.671 ± 0.171
2.173MetLeu: 2.173 ± 0.232
0.376MetMet: 0.376 ± 0.106
0.51MetAsn: 0.51 ± 0.125
0.698MetPro: 0.698 ± 0.125
0.671MetGln: 0.671 ± 0.127
1.315MetArg: 1.315 ± 0.21
1.663MetSer: 1.663 ± 0.202
1.1MetThr: 1.1 ± 0.189
1.476MetVal: 1.476 ± 0.21
0.241MetTrp: 0.241 ± 0.07
0.724MetTyr: 0.724 ± 0.157
0.0MetXaa: 0.0 ± 0.0
Asn
3.139AsnAla: 3.139 ± 0.245
0.698AsnCys: 0.698 ± 0.149
1.556AsnAsp: 1.556 ± 0.178
1.905AsnGlu: 1.905 ± 0.312
1.663AsnPhe: 1.663 ± 0.221
2.629AsnGly: 2.629 ± 0.298
1.02AsnHis: 1.02 ± 0.146
2.764AsnIle: 2.764 ± 0.269
1.583AsnLys: 1.583 ± 0.189
4.4AsnLeu: 4.4 ± 0.32
0.859AsnMet: 0.859 ± 0.175
1.932AsnAsn: 1.932 ± 0.285
2.361AsnPro: 2.361 ± 0.217
1.315AsnGln: 1.315 ± 0.232
2.012AsnArg: 2.012 ± 0.257
2.925AsnSer: 2.925 ± 0.311
2.925AsnThr: 2.925 ± 0.304
3.381AsnVal: 3.381 ± 0.338
0.51AsnTrp: 0.51 ± 0.137
1.583AsnTyr: 1.583 ± 0.202
0.0AsnXaa: 0.0 ± 0.0
Pro
4.588ProAla: 4.588 ± 0.414
1.207ProCys: 1.207 ± 0.173
2.683ProAsp: 2.683 ± 0.268
3.568ProGlu: 3.568 ± 0.387
2.093ProPhe: 2.093 ± 0.19
5.286ProGly: 5.286 ± 0.73
2.012ProHis: 2.012 ± 0.308
3.059ProIle: 3.059 ± 0.27
2.522ProLys: 2.522 ± 0.301
5.286ProLeu: 5.286 ± 0.415
0.966ProMet: 0.966 ± 0.281
1.905ProAsn: 1.905 ± 0.234
6.171ProPro: 6.171 ± 0.854
2.442ProGln: 2.442 ± 0.291
3.917ProArg: 3.917 ± 0.612
4.99ProSer: 4.99 ± 0.528
4.051ProThr: 4.051 ± 0.439
5.447ProVal: 5.447 ± 0.482
0.966ProTrp: 0.966 ± 0.165
1.342ProTyr: 1.342 ± 0.218
0.0ProXaa: 0.0 ± 0.0
Gln
3.059GlnAla: 3.059 ± 0.429
1.127GlnCys: 1.127 ± 0.174
1.771GlnAsp: 1.771 ± 0.27
1.556GlnGlu: 1.556 ± 0.253
1.422GlnPhe: 1.422 ± 0.304
2.281GlnGly: 2.281 ± 0.242
0.966GlnHis: 0.966 ± 0.177
2.039GlnIle: 2.039 ± 0.237
1.503GlnLys: 1.503 ± 0.179
3.273GlnLeu: 3.273 ± 0.258
0.671GlnMet: 0.671 ± 0.134
1.368GlnAsn: 1.368 ± 0.191
2.254GlnPro: 2.254 ± 0.273
1.637GlnGln: 1.637 ± 0.284
2.254GlnArg: 2.254 ± 0.26
2.442GlnSer: 2.442 ± 0.288
3.246GlnThr: 3.246 ± 0.341
2.334GlnVal: 2.334 ± 0.415
0.51GlnTrp: 0.51 ± 0.145
1.181GlnTyr: 1.181 ± 0.211
0.0GlnXaa: 0.0 ± 0.0
Arg
5.017ArgAla: 5.017 ± 0.361
1.717ArgCys: 1.717 ± 0.26
3.381ArgAsp: 3.381 ± 0.294
3.112ArgGlu: 3.112 ± 0.398
2.254ArgPhe: 2.254 ± 0.261
4.615ArgGly: 4.615 ± 0.364
1.717ArgHis: 1.717 ± 0.247
2.549ArgIle: 2.549 ± 0.253
2.093ArgLys: 2.093 ± 0.246
6.547ArgLeu: 6.547 ± 0.4
0.832ArgMet: 0.832 ± 0.185
2.039ArgAsn: 2.039 ± 0.249
3.407ArgPro: 3.407 ± 0.312
2.361ArgGln: 2.361 ± 0.258
4.373ArgArg: 4.373 ± 0.394
4.454ArgSer: 4.454 ± 0.58
3.005ArgThr: 3.005 ± 0.302
4.508ArgVal: 4.508 ± 0.345
1.368ArgTrp: 1.368 ± 0.541
1.449ArgTyr: 1.449 ± 0.231
0.0ArgXaa: 0.0 ± 0.0
Ser
6.171SerAla: 6.171 ± 0.396
1.556SerCys: 1.556 ± 0.186
3.649SerAsp: 3.649 ± 0.359
3.354SerGlu: 3.354 ± 0.304
2.71SerPhe: 2.71 ± 0.349
5.017SerGly: 5.017 ± 0.584
2.12SerHis: 2.12 ± 0.33
3.542SerIle: 3.542 ± 0.327
2.334SerLys: 2.334 ± 0.285
7.459SerLeu: 7.459 ± 0.548
1.556SerMet: 1.556 ± 0.205
2.898SerAsn: 2.898 ± 0.273
5.366SerPro: 5.366 ± 0.766
2.737SerGln: 2.737 ± 0.3
4.749SerArg: 4.749 ± 0.33
5.903SerSer: 5.903 ± 0.561
3.729SerThr: 3.729 ± 0.35
5.259SerVal: 5.259 ± 0.409
0.751SerTrp: 0.751 ± 0.153
1.824SerTyr: 1.824 ± 0.215
0.0SerXaa: 0.0 ± 0.0
Thr
4.695ThrAla: 4.695 ± 0.559
1.529ThrCys: 1.529 ± 0.266
3.059ThrAsp: 3.059 ± 0.354
3.515ThrGlu: 3.515 ± 0.247
2.71ThrPhe: 2.71 ± 0.267
3.917ThrGly: 3.917 ± 0.33
1.959ThrHis: 1.959 ± 0.219
2.951ThrIle: 2.951 ± 0.265
1.959ThrLys: 1.959 ± 0.294
6.171ThrLeu: 6.171 ± 0.496
1.181ThrMet: 1.181 ± 0.279
2.334ThrAsn: 2.334 ± 0.33
5.205ThrPro: 5.205 ± 0.568
1.985ThrGln: 1.985 ± 0.243
3.971ThrArg: 3.971 ± 0.362
5.071ThrSer: 5.071 ± 0.334
4.588ThrThr: 4.588 ± 0.507
5.447ThrVal: 5.447 ± 0.391
1.181ThrTrp: 1.181 ± 0.16
2.388ThrTyr: 2.388 ± 0.348
0.0ThrXaa: 0.0 ± 0.0
Val
5.661ValAla: 5.661 ± 0.51
2.307ValCys: 2.307 ± 0.317
3.676ValAsp: 3.676 ± 0.325
2.817ValGlu: 2.817 ± 0.293
4.159ValPhe: 4.159 ± 0.331
3.703ValGly: 3.703 ± 0.628
1.69ValHis: 1.69 ± 0.21
3.488ValIle: 3.488 ± 0.339
2.79ValLys: 2.79 ± 0.321
6.627ValLeu: 6.627 ± 0.443
1.556ValMet: 1.556 ± 0.173
3.112ValAsn: 3.112 ± 0.306
4.883ValPro: 4.883 ± 0.5
2.415ValGln: 2.415 ± 0.445
4.132ValArg: 4.132 ± 0.348
5.5ValSer: 5.5 ± 0.463
5.339ValThr: 5.339 ± 0.441
5.178ValVal: 5.178 ± 0.461
0.51ValTrp: 0.51 ± 0.129
2.925ValTyr: 2.925 ± 0.306
0.0ValXaa: 0.0 ± 0.0
Trp
1.02TrpAla: 1.02 ± 0.175
0.483TrpCys: 0.483 ± 0.1
0.483TrpAsp: 0.483 ± 0.138
0.51TrpGlu: 0.51 ± 0.111
0.671TrpPhe: 0.671 ± 0.143
1.181TrpGly: 1.181 ± 0.722
0.376TrpHis: 0.376 ± 0.116
0.563TrpIle: 0.563 ± 0.112
0.563TrpLys: 0.563 ± 0.124
1.69TrpLeu: 1.69 ± 0.257
0.215TrpMet: 0.215 ± 0.077
0.617TrpAsn: 0.617 ± 0.113
0.698TrpPro: 0.698 ± 0.133
0.537TrpGln: 0.537 ± 0.105
0.563TrpArg: 0.563 ± 0.121
0.644TrpSer: 0.644 ± 0.15
0.778TrpThr: 0.778 ± 0.137
0.617TrpVal: 0.617 ± 0.142
0.054TrpTrp: 0.054 ± 0.039
0.295TrpTyr: 0.295 ± 0.08
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.656TyrAla: 2.656 ± 0.261
1.046TyrCys: 1.046 ± 0.164
1.395TyrAsp: 1.395 ± 0.23
1.395TyrGlu: 1.395 ± 0.181
1.583TyrPhe: 1.583 ± 0.166
2.066TyrGly: 2.066 ± 0.226
0.698TyrHis: 0.698 ± 0.158
1.476TyrIle: 1.476 ± 0.215
1.342TyrLys: 1.342 ± 0.21
3.542TyrLeu: 3.542 ± 0.321
0.805TyrMet: 0.805 ± 0.172
1.476TyrAsn: 1.476 ± 0.221
1.127TyrPro: 1.127 ± 0.141
1.073TyrGln: 1.073 ± 0.245
1.717TyrArg: 1.717 ± 0.23
2.361TyrSer: 2.361 ± 0.229
1.422TyrThr: 1.422 ± 0.196
2.576TyrVal: 2.576 ± 0.304
0.322TyrTrp: 0.322 ± 0.12
1.02TyrTyr: 1.02 ± 0.218
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 95 proteins (37272 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski